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” He and Munakata feel that gradual improvements in the way in which the DNA is saved may lead to the loss of fertility as Ladies age. If that's so, their analysis could pave the way for enhanced treatment method and diagnosis of fertility complications.
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Using the GCRLE grant, Munakata and Namekawa will seem more carefully at how oocytes are genomically primed and stored for afterwards use. They may investigate the part of a chromatin remodeler in oocyte survival and fertility.
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Namekawa thinks that in human oocytes, alterations in these patterns could disrupt the fragile choreography of genes remaining turned on and off at the right instances — leaving them unprepared for fertilization or advancement into balanced embryos. Alterations in chromatin composition being an oocyte ages may additionally impression the way in which that chromosomes segregate through cell division.
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