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“If we know the way this chromatin point out is proven, and how it relates to oocyte high-quality, it could eventually bring on therapies for a few types of infertility,” claims Namekawa.
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This might enable make clear why more mature Girls usually tend to bear children with chromosomal Problems like Down Syndrome, during which an additional copy of chromosome 21 finds its way into an oocyte — and afterwards, an embryo.
Munakata and Namekawa will Review mice with normal and mutated versions of the chromatin remodeler. Given that the mice mature and experienced, they'll notice if the presence or absence of this protein triggers differences inside the arrangement of DNA spools in the animals’ oocytes. And they'll keep an eye on whether this, consequently, alters the sample of gene expression with time.
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